942475-04-9

Basic information

• Product Name: 4-(2,4-DIFLUORO-PHENYL)-3-OXO-BUTYRIC ACID METHYL ESTER
• Synonyms: 4-(2,4-DIFLUORO-PHENYL)-3-OXO-BUTYRIC ACID METHYL ESTER;2,4-DIFLUORO-BETA-OXO-BENZENEBUTANOIC ACID METHYL ESTER;Methyl 2,4-difluoro-b-oxo-benzenebutanate
• CAS NO: 942475-04-9
• Molecular Formula: C₁₁H₁₀F₂O₃
• Molecular Weight: 228.19
• Mol File: 942475-04-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 274.0±30.0 °C(Predicted)
• Appearance: /
• Density: 1.262±0.06 g/cm3(Predicted)
• PKA: 10.17±0.46(Predicted)
• CAS DataBase Reference: 4-(2,4-DIFLUORO-PHENYL)-3-OXO-BUTYRIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,4-DIFLUORO-PHENYL)-3-OXO-BUTYRIC ACID METHYL ESTER(942475-04-9)
• EPA Substance Registry System: 4-(2,4-DIFLUORO-PHENYL)-3-OXO-BUTYRIC ACID METHYL ESTER(942475-04-9)

Safety Data

• Hazardous Substances Data: 942475-04-9(Hazardous Substances Data)

Upstream product

• 81228-09-3 2,4-difluorophenylacetic acid 
• 67-56-1 methanol 

Downstream Products

• 851307-12-5 3-tert-butoxycarbonylamino-4-(2,4-difluoro-phenyl)-butyric acid 
• 945261-73-4 C₁₉H₂₀F₂N₂O₃ 

Relevant articles and documents

Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA (sitagliptin phosphate)

A series of β-aminoamides bearing triazolopiperazines has been prepared and evaluated as potent, selective, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. Efforts at optimization of the β-aminoamide series, which ultimately led to the discovery