942589-45-9

Basic information

• Product Name: Methyl 3-aMino-5-iodo-2-thiophenecarboxylate
• Synonyms: Methyl 3-aMino-5-iodo-2-thiophenecarboxylate;3-Amino-5-iodo-2-thiophenecarboxylic acid methyl ester;methyl 3-amino-5-iodothiophene-2-carboxylate hydrochloride;2-Thiophenecarboxylic acid, 3-amino-5-iodo-, methyl ester
• CAS NO: 942589-45-9
• Molecular Formula: C₆H₆INO₂S
• Molecular Weight: 283.08681
• Mol File: 942589-45-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Methyl 3-aMino-5-iodo-2-thiophenecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-aMino-5-iodo-2-thiophenecarboxylate(942589-45-9)
• EPA Substance Registry System: Methyl 3-aMino-5-iodo-2-thiophenecarboxylate(942589-45-9)

Safety Data

• Hazardous Substances Data: 942589-45-9(Hazardous Substances Data)

Usage

General Description

Methyl 3-amino-5-iodo-2-thiophenecarboxylate is a chemical compound that consists of a methyl ester functional group, an amino group, an iodine atom, and a thiophene ring. The compound has potential applications in pharmaceuticals as an intermediate in the synthesis of certain drugs. What makes it valuable is the presence of an iodine atom, which is often used in radiographic imaging and radiotherapy. The specific properties of Methyl 3-amino-5-iodo-2-thiophenecarboxylate, including its reactivity and stability, are strongly determined by the interplay of these functional groups and elements. However, the safety, toxicity, and environmental impacts of this compound are not well studied and should be evaluated before any significant use.

InChI:InChI=1S/C6H6INO2S/c1-10-6(9)5-3(8)2-4(7)11-5/h2H,8H2,1H3

Upstream product

• 149587-72-4 3-(tert-butoxycarboxamido)thiophen-2-formic acid methyl ester 
• 79128-68-0 methyl 3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate 
• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 
• 1019338-24-9 methyl 3-(bis{[(1,1-dimethylethyl)oxy]carbonyl}amino)-5-iodo-2-thiophenecarboxylate 
• 942589-44-8 methyl 5-iodo-3-[(2,2,2-trifluoroacetyl)amino]thiophene-2-carboxylate 
• 1007171-35-8 methyl 3-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5-iodo-2-thiophenecarboxylate 

Downstream Products

• 1019338-25-0 methyl 3-{[(4-chloro-2-fluorophenyl)carbonyl]amino}-5-iodo-2-thiophenecarboxylate 
• 1027708-01-5 methyl 3-(trans-4-methylcyclohexylcarbonylamino)-5-iodothiophene-2-carboxylate 

Relevant articles and documents

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The hepatitis C viral proteins NS3/4A protease, NS5B polymerase, and NS5A are clinically validated targets for direct-acting antiviral therapies. The NS5B polymerase may be inhibited directly through the action of nucleosides or nucleotide analogues or al

COMPOUNDS

Anti-viral agents of compounds of Formula (I) : wherein A, R1, R2 and R3 are as defined in the specification, processes for their preparation and their use in HCV treatment are provided.

ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS

Anti-viral agents of compounds of Formula (I) : wherein A, R1, R2 and R3 are as defined in the specification, processes for their preparation and their use in HCV treatment are provided.