942924-77-8

Basic information

• Product Name: [2-oxo-1-(4-phenylbutyl)-1,2,5,6-tetrahydropyridin-3-yl]acetic acid methyl ester
• Synonyms: [2-oxo-1-(4-phenylbutyl)-1,2,5,6-tetrahydropyridin-3-yl]acetic acid methyl ester
• CAS NO: 942924-77-8
• Molecular Weight: 301.386
• Mol File: 942924-77-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-oxo-1-(4-phenylbutyl)-1,2,5,6-tetrahydropyridin-3-yl]acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-oxo-1-(4-phenylbutyl)-1,2,5,6-tetrahydropyridin-3-yl]acetic acid methyl ester(942924-77-8)
• EPA Substance Registry System: [2-oxo-1-(4-phenylbutyl)-1,2,5,6-tetrahydropyridin-3-yl]acetic acid methyl ester(942924-77-8)

Safety Data

• Hazardous Substances Data: 942924-77-8(Hazardous Substances Data)

Upstream product

• 13214-66-9 4-phenyl-1-butylamine 
• 7338-27-4 4-methoxy-2-methylene-4-oxobutanoic acid 
• 942924-64-3 C₁₄H₂₁N 
• 942924-68-7 3-[but-3-enyl-(4-phenylbutyl)carbamoyl]but-3-enoic acid methyl ester 

Relevant articles and documents

Structure-activity relationship studies of a series of novel δ-lactam-based histone deacetylase inhibitors

We synthesized a series of δ-lactam-based HDAC inhibitors that were identified with various degrees of anti-inflammatory and cell growth inhibitory activities. Compounds possessing significant HDAC inhibitory activity exhibited both anti-inflammatory and cell growth inhibitory activities as well as significant tumor growth inhibition in the in vivo tumor xenograft experiments. Besides, these compounds demonstrated antiinflammatory properties in vitro via suppression of the production of the proinflammatory cytokine TNF-α and nitric oxide by LPS-stimulated RAW264.7 cells.