94345-95-6

Basic information

• Product Name: L-Tyrosine,3,5-diiodo-o-(4-Methoxyphenyl)
• Synonyms: L-Tyrosine,3,5-diiodo-o-(4-Methoxyphenyl);Levothyroxine Related Compound (2-Amino-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl)propanoic acid);Levothyroxine Sodium Impurity 11
• CAS NO: 94345-95-6
• Molecular Formula: C₁₆H₁₅I₂NO₄
• Molecular Weight: 539.10354
• EINECS: -0
• Mol File: 94345-95-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.98[at 20℃]
• Vapor Pressure: 0Pa at 25℃
• CAS DataBase Reference: L-Tyrosine,3,5-diiodo-o-(4-Methoxyphenyl)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tyrosine,3,5-diiodo-o-(4-Methoxyphenyl)(94345-95-6)
• EPA Substance Registry System: L-Tyrosine,3,5-diiodo-o-(4-Methoxyphenyl)(94345-95-6)

Safety Data

• Hazardous Substances Data: 94345-95-6(Hazardous Substances Data)

Usage

Flammability and Explosibility

Notclassified

Upstream product

• 300-39-0 3,5-diiodo-l-tyrosine 
• 6293-71-6 4,4'-dimethoxydiphenyliodonium iodide 
• 83249-56-3 N-acetyl-O-(4-methoxyphenyl)-3,5-diiodo-L-tyrosine ethyl ester 
• 60-18-4 L-tyrosine 
• 49553-16-4 {Cu(HOC₆H₂I₂CH₂CH(NH₂)COO)2} 
• 19231-06-2 4,4'-dimethoxy-diphenyliodonium bromide 
• 83290-90-8 3.5-dinitro-O'-methyl-N-acetyl-L-thyronine ethyl ester 
• 440667-78-7 3.5-diamino-O'-methyl-N-acetyl-L-thyronine ethyl ester 
• 886203-79-8 N-acetyl-3,5-diiodo-O'-methyl-L-thyronine 
• 17360-11-1 NSC 80662 
• 29358-99-4 N-acetyl-3,5-dinitro-L-tyrosine ethyl ester 
• 20767-00-4 3.5-Dinitro-N-acetyl-L-tyrosin 

Downstream Products

• 70-40-6 3,3′-diiodothyronine 
• 51-48-9 L-thyroxine 
• 55-03-8 L-thyroxine sodium 
• 1041-01-6 3,5-diiodo-L-thyronine 

Relevant articles and documents

Improved method for synthesizing L-thyroxine sodium

The invention relates to an improved method for synthesizing L-thyroxine sodium. The improved method includes the steps that 3,5-diiodomethane-L-tyrosine is used as a raw material, and then subjectedto a copper complex reaction, a coupling reaction, an acid hydrolysis reaction, an iodine generation reaction and a salt forming reaction to obtained the L-thyroxine sodium. According to the improvedmethod for synthesizing the L-thyroxine sodium, the yield of the L-thyroxine sodium can be improved, the product cost is lowered, and industrialization is convenient.