94347-46-3Relevant articles and documents
Lipase catalysed synthesis of optically enriched α-haloamides
Azim, Abul,Sharma, Sunil K.,Olsen, Carl E.,Parmar, Virinder S.
, p. 1345 - 1348 (2007/10/03)
An efficient lipase catalysed synthesis of optically enriched α-halogenated amides with concomitant optical enrichment of the starting α-haloesters is described. Candida antarctica lipase (CAL) was found to be a better catalyst over porcine pancreatic lipase (PPL) and Candida cylindracea lipase (CCL). The effect of different organic solvents was also studied.
Enzymatic Aminolysis and Transamidation Reactions
Gotor, Vicente,Brieva, Rosario,Gonzalez, Carmen,Rebolledo, Francisca
, p. 9207 - 9214 (2007/10/02)
Chiral amides can be obtained from (+/-)-2-chloropropionate esters and a wide range of amines when the reaction is catalyzed by Candida cylindracea lipase.The enantioselection of the enzyme in this aminolysis reaction depends on the substrate and nucleoph