94360-90-4

Basic information

• Product Name: 3-Pyridinecarbonitrile, 2-[[2-(4-fluorophenyl)-2-oxoethyl]thio]-4,6-diphenyl-
• CAS NO: 94360-90-4
• Molecular Formula: C26H17FN2OS
• Molecular Weight: 424.498
• Mol File: 94360-90-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarbonitrile, 2-[[2-(4-fluorophenyl)-2-oxoethyl]thio]-4,6-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 2-[[2-(4-fluorophenyl)-2-oxoethyl]thio]-4,6-diphenyl-(94360-90-4)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 2-[[2-(4-fluorophenyl)-2-oxoethyl]thio]-4,6-diphenyl-(94360-90-4)

Safety Data

• Hazardous Substances Data: 94360-90-4(Hazardous Substances Data)

Upstream product

• 58327-74-5 4,6-diphenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 403-29-2 2-bromo-4'-fluoroacetophenone 

Downstream Products

• 94360-98-2 (3-Amino-4,6-diphenyl-thieno[2,3-b]pyridin-2-yl)-(4-fluoro-phenyl)-methanone 

Relevant articles and documents

CYCLIZATION OF NITRILES. IX. SYNTHESES BASED ON 2-ARYL-3-AROYL-1,1-DICYANOPROPANES

2-Aryl-3-aroyl-1,1-dicyanopropanes and 2-aryl-3-aroyl-1-bromo-1,1-dicyanopropanes were synthesized from chalcones and malononitrile and were converted into 4,6-diaryl-2-bromo-3-cyanopyridines and 3-cyano-2(1H)-pyridinethiones.The 2-aryl-3-aroyl-1-bromo-1,1-dicyanopropanes proved convenient intermediates for the production of the corresponding cyclopropanes and other compounds.By their reaction with urea a new method was developed for the production of substituted 3-cyano-2(1H)-pyridinethiones.The 2-bromo-3-cyanopyridines contain a mobile bromine atom readily exchanged for the various nucleophilic residues of alcohols and amines and for iodide, and cyano and thiocyanato groups.The 3-cyano-2(1H)-pyridinethiones were used in the synthesis of 3-aminothienopyridines through the isolated 2-Z-methylthio-3-cyanopyridines.