943606-89-1

Basic information

• Product Name: 7-methyl-N⁴-(3-(trifluoromethyl)phenyl)quinazoline-4,8-diamine
• Synonyms: 7-methyl-N⁴-(3-(trifluoromethyl)phenyl)quinazoline-4,8-diamine
• CAS NO: 943606-89-1
• Molecular Weight: 318.301
• Mol File: 943606-89-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-methyl-N⁴-(3-(trifluoromethyl)phenyl)quinazoline-4,8-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methyl-N⁴-(3-(trifluoromethyl)phenyl)quinazoline-4,8-diamine(943606-89-1)
• EPA Substance Registry System: 7-methyl-N⁴-(3-(trifluoromethyl)phenyl)quinazoline-4,8-diamine(943606-89-1)

Safety Data

• Hazardous Substances Data: 943606-89-1(Hazardous Substances Data)

Upstream product

• 50424-81-2 4-methyl-2-nitro-benzoyl chloride 
• 1449737-59-0 5-bromo-4-chloro-7-methyl-8-nitroquinazoline 
• 1449737-57-8 5-bromo-7-methyl-8-nitroquinazolin-4(3H)-one 
• 1449737-56-7 5-bromo-7-methylquinazolin-4(3H)-one 
• 75844-40-5 7-methyl-quinazolin-4(3H)-one 
• 39549-79-6 2-amino-4-methylbenzamide 
• 65078-05-9 4-methyl-2-nitrobenzamide 
• 27329-27-7 4-methyl-2-nitrobenzoic acid 
• 1449737-58-9 5-bromo-7-methyl-8-nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine 
• 943605-88-7 6-bromo-7-methyl-8-nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine 

Relevant articles and documents

BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.