943617-66-1Relevant articles and documents
Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2
Ortiz Zacarías, Natalia V.,Chahal, Kirti K.,?imková, Tereza,Van Der Horst, Cas,Zheng, Yi,Inoue, Asuka,Theunissen, Emy,Mallee, Lloyd,Van Der Es, Daan,Louvel, Julien,Ijzerman, Adriaan P.,Handel, Tracy M.,Kufareva, Irina,Heitman, Laura H.
, p. 2608 - 2621 (2021/03/09)
Covalently acting inhibitors constitute a large and growing fraction of approved small-molecule therapeutics as well as useful tools for a variety of in vitro and in vivo applications. Here, we aimed to develop a covalent antagonist of CC chemokine recept
ANTI-VIRAL COMPOUNDS
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Page/Page column 78, (2008/12/08)
Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.