943740-09-8

Basic information

• Product Name: 4-(4-(3-cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid
• Synonyms: 4-(4-(3-cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid
• CAS NO: 943740-09-8
• Molecular Weight: 400.263
• Mol File: 943740-09-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-(3-cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-(3-cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid(943740-09-8)
• EPA Substance Registry System: 4-(4-(3-cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid(943740-09-8)

Safety Data

• Hazardous Substances Data: 943740-09-8(Hazardous Substances Data)

Upstream product

• 918810-26-1 2-(Ethylthio)-5-nitrobenzonitrile 
• 17417-09-3 2-fluoro-5-nitrobenzonitrile 
• 943740-08-7 4-(4-bromophenyl)-N-(3-cyano-4-(ethylsulfonyl)phenyl)butanamide 
• 918812-59-6 5-amino-2-(ethylsulfonyl)benzonitrile 
• 918810-27-2 2-(ethylsulfonyl)-5-nitrobenzonitrile 
• 22647-95-6 5-(4-bromophenyl)pentanoic acid 
• 6628-03-1 4-(4-bromophenyl)-butyryl chloride 
• 201733-56-4 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane 

Downstream Products

• 943740-10-1 2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(4-(4-(3-cyano-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenyl)acetic acid 

Relevant articles and documents

Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors

On the basis of a crystal structure of a phenylpyrrolidine lead and subsequent molecular modeling results, we designed and synthesized a novel series of macrocyclic FVIIa inhibitors. The optimal 16-membered macrocycle was 60-fold more potent than an acycl