943740-18-9

Basic information

• Product Name: 4-(4-bromophenyl)-N-(3-cyano-4-(isopropylsulfonyl)phenyl)butanamide
• CAS NO: 943740-18-9
• Molecular Weight: 449.368
• Mol File: 943740-18-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-bromophenyl)-N-(3-cyano-4-(isopropylsulfonyl)phenyl)butanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-bromophenyl)-N-(3-cyano-4-(isopropylsulfonyl)phenyl)butanamide(943740-18-9)
• EPA Substance Registry System: 4-(4-bromophenyl)-N-(3-cyano-4-(isopropylsulfonyl)phenyl)butanamide(943740-18-9)

Safety Data

• Hazardous Substances Data: 943740-18-9(Hazardous Substances Data)

Upstream product

• 948992-52-7 2-(isopropylthio)-5-nitrobenzonitrile 
• 17417-09-3 2-fluoro-5-nitrobenzonitrile 
• 918813-36-2 2-(isopropylsulfonyl)-5-nitrobenzonitrile 
• 22647-95-6 5-(4-bromophenyl)pentanoic acid 
• 918813-12-4 5-amino-2-(isopropylsulfonyl)benzonitrile 
• 6628-03-1 4-(4-bromophenyl)-butyryl chloride 

Downstream Products

• 943740-20-3 4-(4-(3-cyano-4-(isopropylsulfonyl)phenylamino)-4-oxobutyl)phenylboronic acid 
• 943740-21-4 2-(1-di-tert-butoxycarbonylaminoisoquinolin-6-ylamino)-2-(4-(4-(3-cyano-4-(isopropylsulfonyl)phenylamino)-4-oxobutyl)phenyl)acetic acid 
• 943740-19-0 N-(3-cyano-4-(isopropylsulfonyl)phenyl)-4-(4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)butanamide 

Relevant articles and documents

Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors

On the basis of a crystal structure of a phenylpyrrolidine lead and subsequent molecular modeling results, we designed and synthesized a novel series of macrocyclic FVIIa inhibitors. The optimal 16-membered macrocycle was 60-fold more potent than an acycl