943963-85-7Relevant articles and documents
Preparation of spiro [benzoisothiazole-isoxazole] dioxides from dilithiated C(α),O-oximes and methyl 2-(aminosulfonyl)benzoate
Grant, Bonnie J.,Kramp, Catherine R.,Knight, John D.,Meierhoefer, Michelle A.,Vella, Jarrett H.,Sober, Carolyn L.,Jones, Stephen S.,Metz, Clyde R.,Beam, Charles F.,Pennington, William T.,VanDerveer, Donald G.,Camper, N. Dwight
, p. 627 - 632 (2008/09/18)
Several dilithiated C(α),O-oximes were prepared in excess lithium diisopropylamide-tetramethyl-ethylenediamine (LDA/TMEDA) and condensed with methyl 2-(aminosulfonyl)benzoate followed by acid cyclization of intermediates to spiro(benzoisothiazole-isoxazol