945292-58-0

Basic information

• Product Name: (S)-2-Hydroxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid
• CAS NO: 945292-58-0
• Molecular Weight: 408.451
• Mol File: 945292-58-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-Hydroxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Hydroxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid(945292-58-0)
• EPA Substance Registry System: (S)-2-Hydroxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid(945292-58-0)

Safety Data

• Hazardous Substances Data: 945292-58-0(Hazardous Substances Data)

Upstream product

• 137173-40-1 (2S,3R)-methyl p-methoxycinnamate epoxide 
• 123-11-5 4-methoxy-benzaldehyde 
• 856899-98-4 methyl 2-dihydroxy-3-(4-methoxyphenyl)propanoate 
• 23508-35-2 (S)-2-hydroxy-3-(4-hydroxy-phenyl)-propionic acid 
• 179020-04-3 4-(3-chloropropoxy)-O-phenylphenol 

Relevant articles and documents

An asymmetric synthesis of PPAR-γ agonist navaglitazar from (+)-methyl (2S,3R)-3-(4-methoxyphenyl)glycidate

An asymmetric synthesis of navaglitazar, a peroxisome proliferator activated receptor (PPAR) γ agonist, from commercially available (+)-methyl (2S,3R)-3-(4-methoxyphenyl)glycidate, is described. The new synthesis features high overall yield, low solvent usage, crystalline intermediates and operational simplicity. Schweizerische Chemische Gesellschaft.