945389-41-3 Usage
Description
2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-1H-imidazole is a novel 2-imidazole derivative that exhibits potent and selective activity as an α1A adrenoceptor partial agonist.
Uses
Used in Pharmaceutical Industry:
2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-1H-imidazole is used as a pharmaceutical agent for the treatment of various conditions, particularly those related to the α1A adrenoceptor. Its selective agonist properties make it a promising candidate for developing targeted therapies with fewer side effects.
Used in Research Applications:
In the field of scientific research, 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-1H-imidazole serves as a valuable tool for studying the role and function of the α1A adrenoceptor. It can be utilized in experiments to investigate the mechanisms of action and potential therapeutic applications related to this receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 945389-41-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,5,3,8 and 9 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 945389-41:
(8*9)+(7*4)+(6*5)+(5*3)+(4*8)+(3*9)+(2*4)+(1*1)=213
213 % 10 = 3
So 945389-41-3 is a valid CAS Registry Number.
945389-41-3Relevant articles and documents
Novel 2-imidazoles as potent and selective α1A adrenoceptor partial agonists
Whitlock, Gavin A.,Conlon, Kelly,McMurray, Gordon,Roberts, Lee R.,Stobie, Alan,Thurlow, Richard J.
, p. 2930 - 2934 (2008/12/22)
Novel 2-imidazoles have been identified as potent partial agonists of the α1A adrenergic receptor, with good selectivity over the α1B, α1D and α2A receptor sub-types. Sulfonamide 23 possessed attractive drug-like properties with respect to physicochemical and ADME properties and wide ligand selectivity.
