945483-25-0

Basic information

• Product Name: methyl (E)-(N-allyl-N-benzylamino)but-2-enoate
• Synonyms: methyl (E)-(N-allyl-N-benzylamino)but-2-enoate
• CAS NO: 945483-25-0
• Molecular Weight: 245.321
• Mol File: 945483-25-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (E)-(N-allyl-N-benzylamino)but-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (E)-(N-allyl-N-benzylamino)but-2-enoate(945483-25-0)
• EPA Substance Registry System: methyl (E)-(N-allyl-N-benzylamino)but-2-enoate(945483-25-0)

Safety Data

• Hazardous Substances Data: 945483-25-0(Hazardous Substances Data)

Upstream product

• 4383-22-6 Allylbenzylamine 
• 1117-71-1 methyl-4-bromo-2-butenoate 

Downstream Products

• 945483-37-4 methyl (2S,3R,αS)-2-methyl-3-[N-benzyl-N-(α-methylbenzyl)amino]-4-(N'-benzyl-N'-allylamino)butanoate 
• 906750-09-2 methyl (3R,αS)-3-[N-methyl-N-(α-methylbenzyl)amino]-4-(N'-benzyl-N'-allylamino)butanoate 
• 945483-47-6 methyl (2S,3S,αS)-2-hydroxy-3-[N-methyl-N-(α-methylbenzyl)amino]-4-(N'-benzyl-N'-allylamino)butanoate 
• 906750-02-5 methyl (3R,αS)-3-[N-benzyl-N-(α-methylbenzyl)amino]-4-(N'-benzyl-N'-allylamino)butanoate 
• 945483-50-1 (3R,4S,αS)-N(1)-benzyl-3-methoxy-4-[N'-methyl-N'-α-methylbenzylamino]pyrrolidine 
• 945483-49-8 (3S,4S,αS)-N(1)-benzyl-3-methoxy-4-[N'-methyl-N'-α-methylbenzylamino]pyrrolidin-2-one 
• 945483-48-7 methyl (2S,3S,αS)-2-methoxy-3-[N-methyl-N-(α-methylbenzyl)amino]-4-(N'-benzyl-N'-allylamino)butanoate 
• 945483-46-5 (3S,4S,αS)-N(1)-benzyl-3-methoxy-4-[N'-methyl-N'-(α-methylbenzyl)amino]pyrrolidine 
• 945483-45-4 (3R,4S,αS)-N(1)-benzyl-3-methoxy-4-[N'-methyl-N'-(α-methylbenzyl)amino]pyrrolid-2-one 
• 906750-11-6 (3R,4S,αS)-N(1)-benzyl-3-hydroxy-4-[N'-methyl-N'-(α-methylbenzyl)amino]pyrrolid-2-one 
• 906750-10-5 (4R,αS)-N(1)-benzyl-4-[N'-methyl-N'-(α-methylbenzyl)amino]pyrrolid-2-one 
• 906750-03-6 (4R,αS)-N(1)-benzyl-4-[N'-benzyl-N'-(α-methylbenzyl)amino]pyrrolid-2-one 
• 945483-44-3 (3R,4S,αS)-N(1)-benzyl-3-hydroxy-4-[N-benzyl-N-(α-methylbenzyl)amino]pyrrolidine 
• 945483-43-2 (3R,4R,αS)-N(1)-benzyl-3-[N'-benzyl-N'-(α-methylbenzyl)amino]-4-methylpyrrolidine 

Relevant articles and documents

Lithium amide conjugate addition for the asymmetric synthesis of 3-aminopyrrolidines

Conjugate addition of homochiral lithium amides to methyl 4-(N-benzyl-N-allylamino)but-2-enoate, chemoselective N-deprotection and concomitant cyclisation, followed by enolate functionalisation and deprotection allows access to syn- and anti-3,4-disubstituted aminopyrrolidines in > 98% d.e. and > 98% e.e. The Royal Society of Chemistry 2006.