945652-92-6

Basic information

• Product Name: 2-aminoquinolin-8-yl-4-methylbenzenesulfonate
• Synonyms: 2-aminoquinolin-8-yl-4-methylbenzenesulfonate
• CAS NO: 945652-92-6
• Molecular Weight: 314.365
• Mol File: 945652-92-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-aminoquinolin-8-yl-4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aminoquinolin-8-yl-4-methylbenzenesulfonate(945652-92-6)
• EPA Substance Registry System: 2-aminoquinolin-8-yl-4-methylbenzenesulfonate(945652-92-6)

Safety Data

• Hazardous Substances Data: 945652-92-6(Hazardous Substances Data)

Upstream product

• 70125-16-5 2-amino-8-quinolinol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1146771-54-1 2,2-dimethyl-5-[8-(4-methylbenzenesulfonate)quinolin-2-ylamino]-methylene-1,3-dioxane-4,6-dione 

Relevant articles and documents

Chemoselective acylation of 2-amino-8-quinolinol in the generation of C2-amides or C8-esters

Two different ways to carry out the chemoselective acylation of 2-amino-8-quinolinol with unique features to generate C2-amides or C8-esters were developed. The coupling reaction with a variety of carboxylic acids using EDCI and DMAP provided C8-ester derivatives, whereas N-heteroaromatic acids were not introduced on the C8-hydroxy group, but rather on the C2-amino group under the same conditions. To obtain C2-amides selectively, the anionic nucleophile from 2-amino-8-quinolinol was treated with less reactive acyl imidazolides or esters.