94579-07-4

Basic information

• Product Name: 3-(Dibenzoylamino)-2-pyrazinecarboxylic acid methyl ester
• Synonyms: 3-(Dibenzoylamino)-2-pyrazinecarboxylic acid methyl ester
• CAS NO: 94579-07-4
• Molecular Formula: C₂₀H₁₅N₃O₄
• Molecular Weight: 361.3508
• Mol File: 94579-07-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(Dibenzoylamino)-2-pyrazinecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Dibenzoylamino)-2-pyrazinecarboxylic acid methyl ester(94579-07-4)
• EPA Substance Registry System: 3-(Dibenzoylamino)-2-pyrazinecarboxylic acid methyl ester(94579-07-4)

Safety Data

• Hazardous Substances Data: 94579-07-4(Hazardous Substances Data)

Upstream product

• 16298-03-6 Methyl 3-amino-2-pyrazinecarboxylate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 93044-39-4 3-benzoylamino-pyrazine-2-carboxylic acid methyl ester 
• 23120-10-7 2-phenylpteridin-4(3H)-one 
• 155513-85-2 2-Phenylpyrazino<2,3-d><3,1>oxazin-4-one 

Relevant articles and documents

Dihalogentriphenylphosphoranes in the synthesis of heterocycles, 29. A simple synthesis of pteridin-4-ones, from methyl-3-amino-2-pyrazinecarboxylate and pyrazino[3,1]oxazin-4-ones

Methyl 3-amino-2-pyrazinecarboxylate (3) affords the synthetically useful 3-aroylaminopyrazin-2-carboxylates 5a-f with aroyl chlorides, which are converted with dibromotriphenylphosphorane into 2-arylpyrazino[2,3-d][3,1]oxazin-4-ones 6a-f. Nucleophilic attack at the carbonyl function of these oxazinones results in ring cleaved amides which can be recyclized with dibromotriphenylphosphorane to afford 2-arylpteridin-4-ones 7a-f.