945985-19-3

Basic information

• Product Name: C₂₁H₃₀O₄SSi
• Synonyms: C₂₁H₃₀O₄SSi
• CAS NO: 945985-19-3
• Molecular Weight: 406.618
• Mol File: 945985-19-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₃₀O₄SSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₃₀O₄SSi(945985-19-3)
• EPA Substance Registry System: C₂₁H₃₀O₄SSi(945985-19-3)

Safety Data

• Hazardous Substances Data: 945985-19-3(Hazardous Substances Data)

Upstream product

• 40434-87-5 toluene-4-sulfonic acid 2-hydroxy-2-phenylethyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 945985-20-6 C₂₁H₂₆O₅ 

Relevant articles and documents

Design, synthesis, and structure-activity relationship of carbamate-tethered aryl propanoic acids as novel PPARα/γ dual agonists

We have developed a new class of PPARα/γ dual agonists, which show excellent agonistic activity in PPARα/γ transactivation assay. In particular, (R)-9d was identified as a potent PPARα/γ dual agonist with EC50s of 0.377 μM in PPARα and 0.136 μM in PPARγ, respectively. Interestingly, the structure-activity relationship revealed that the stereochemistry of the identified PPARα/γ dual agonists significantly affects their agonistic activities in PPARα than in PPARγ.