946122-05-0

Basic information

• Product Name: 2-AMINO-4-BROMOBENZYL ALCOHOL
• Synonyms: 2-AMINO-4-BROMOBENZYL ALCOHOL;(2-AMINO-4-BROMOPHENYL)METHANOL
• CAS NO: 946122-05-0
• Molecular Formula: C₇H₈BrNO
• Molecular Weight: 202.05
• Mol File: 946122-05-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 347.821°C at 760 mmHg
• Flash Point: 164.156°C
• Appearance: /
• Density: 1.66g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.654
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 14.01±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4-BROMOBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-BROMOBENZYL ALCOHOL(946122-05-0)
• EPA Substance Registry System: 2-AMINO-4-BROMOBENZYL ALCOHOL(946122-05-0)

Safety Data

• Hazardous Substances Data: 946122-05-0(Hazardous Substances Data)

Usage

General Description

2-Amino-4-Bromobenzyl Alcohol is a chemical compound with the molecular formula C7H8BrNO. As suggested by the name, it contains an amino group (-NH2), a bromine atom (Br), and a hydroxy group (-OH) attached to a benzyl group, which is a functional group derived from benzene. This chemical can be used in various synthetic and chemical reactions due to its diverse functional groups. It shows great significance in organic chemistry and pharmaceutical manufacturing. Safety measures should be taken while handling it due to its potential to cause eye and skin irritation.

InChI:InChI=1/C7H8BrNO/c8-6-2-1-5(4-10)7(9)3-6/h1-3,10H,4,9H2

Upstream product

• 20776-50-5 2-amino-4-bromobenzoic acid 
• 135484-83-2 2-amino-4-bromo-benzoic acid methyl ester 
• 22996-19-6 (4-bromo-2-nitrophenyl)methanol 

Relevant articles and documents

Cationic Iridium-Catalyzed Asymmetric Decarbonylative Aryl Addition of Aromatic Aldehydes to Bicyclic Alkenes

We report an unprecedented catalytic protocol for the enantioselective decarbonylative transformation of aryl aldehydes. In this process, the decarbonylation of aldehydes catalyzed by chiral iridium complexes enabled the formation of asymmetric C?C bonds

3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

Provided are cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor, compositions comprising said compounds, and uses of said compounds in the treatment or prevention of diseases in which M4 muscarinic acetylcholine receptors are involved, especially neurological and psychiatric disorders and diseases.

Pd-Catalyzed Three-Component Domino Reaction of Vinyl Benzoxazinanones for Regioselective and Stereoselective Synthesis of Allylic Sulfone-Containing Amino Acid Derivatives

A Pd-catalyzed, highly regioselective and stereoselective three-component domino allylic substitution/N-H carbene insertion reaction under mild conditions is described. This reaction demonstrates a wide substrate scope and satisfactory functional group tolerance, providing a broad range of allylic sulfone-containing amino acid derivatives. Moreover, DBU mediates highly diastereoselective cross-dehydrogenative coupling annulation of allylic sulfones without using peroxides or any metal oxidants. This developed protocol affords 7-membered ring heterocyclic compounds incorporating both sulfone-containing amino acid esters and one quaternary carbon center. Mechanistic studies indicate that an unusual umpolung of glycine occurred in this annulation.