947689-42-1

Basic information

• Product Name: N-(2-iodophenyl)-4-methyl-N-(propa-1,2-dien-1-yl)benzenesulfonamide
• Synonyms: N-(2-iodophenyl)-4-methyl-N-(propa-1,2-dien-1-yl)benzenesulfonamide
• CAS NO: 947689-42-1
• Molecular Weight: 411.263
• Mol File: 947689-42-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(2-iodophenyl)-4-methyl-N-(propa-1,2-dien-1-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-iodophenyl)-4-methyl-N-(propa-1,2-dien-1-yl)benzenesulfonamide(947689-42-1)
• EPA Substance Registry System: N-(2-iodophenyl)-4-methyl-N-(propa-1,2-dien-1-yl)benzenesulfonamide(947689-42-1)

Safety Data

• Hazardous Substances Data: 947689-42-1(Hazardous Substances Data)

Upstream product

• 140666-28-0 N-(2-iodophenyl)4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 615-43-0 2-iodophenylamine 
• 61613-20-5 N-tosyl-2-iodoaniline 
• 106-96-7 propargyl bromide 

Downstream Products

• 1591916-37-8 3-(furan-2-ylmethyl)-1-tosyl-1H-indole 

Relevant articles and documents

Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds

A palladium-catalyzed allenamide carbopalladation/allylation with active methine compounds has been developed. Various indoles and isoquinolinones bearing a quaternary carbon center were achieved with good efficiency, a broad substrate scope and good functional group tolerance. This reaction underwent cascade oxidative addition, carbopalladation, and allylic alkylation, and two new C-C bonds were formed in one pot.

One-pot multi-step cascade protocols toward β-indolyl sulfoximidoyl amidesviaintermolecular trapping of an α-indolylpalladium complex by CO

Various β-indolyl sulfoximidoyl amides were efficiently prepared fromortho-iodoanilines, propargyl bromides, 1 atm of CO, and substitutedNH-sulfoximines, through a palladium-catalyzed indole annulation/carbonyl insertion/C-N bond formation cascade. Mostly good to high yields of the products were obtained through this multi-step, one-pot reaction protocol under very gentle reaction conditions. The obtained β-indolyl sulfoximidoyl amides could be converted into biologically interesting sulfoximine analogues that contain a tryptamine moiety.

A strategy for the synthesis of 2,3-disubstituted indoles starting from N-(o-halophenyl)allenamides

A strategy for the synthesis of 2,3-disubstituted indole derivatives based on an intramolecular carbopalladation-anion capture cascade has been developed, wherein construction of the pyrrole ring and functionalisation of the indole C2 and C3 positions wer