948039-69-8Relevant articles and documents
Label-free detection of protein-protein interactions on biochips
Yeo, Woon-Seok,Min, Dal-Hee,Hsieh, Robert W.,Greene, Geoffrey L.,Mrksich, Milan
, p. 5480 - 5483 (2007/10/03)
(Figure Presented) Eliminating the middle-man: The combination of MALDI-TOF mass spectrometry and self-assembled monolayers on gold (SAMDI) offers a new detection method for protein-ligand (shown) and protein-protein interactions. Proteins and protein complexes are selectively bound to biochips and then directly analyzed by MALDI-TOF MS without the need for labels.