948048-72-4 Usage
Description
(S)-O-phenylphenylalanine, also known as (S)-2-amino-3-phenylpropionic acid, is a chemical compound that features a phenylalanine molecule with an additional phenyl group attached to the alpha carbon. (S)-O-phenylphenylalanine is recognized for its optical activity due to its chiral nature, with the (S) enantiomer being the naturally occurring form. Its unique structure and properties make it a valuable asset in the pharmaceutical and agrochemical industries.
Uses
Used in Pharmaceutical Industry:
(S)-O-phenylphenylalanine is used as a chiral building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the creation of complex molecules with specific biological activities, contributing to the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry:
(S)-O-phenylphenylalanine is utilized as a starting material to produce other chiral amino acids, which are essential components in the construction of peptide molecules. Its role in medicinal chemistry is significant, as it aids in the design and synthesis of novel compounds with potential applications in drug discovery and development.
Used in Development of New Drugs:
(S)-O-phenylphenylalanine's potential applications in the development of new drugs are vast, thanks to its unique structure and properties. Researchers can leverage (S)-O-phenylphenylalanine to create innovative drug candidates that target specific biological pathways or receptors, potentially leading to more effective treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 948048-72-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,8,0,4 and 8 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 948048-72:
(8*9)+(7*4)+(6*8)+(5*0)+(4*4)+(3*8)+(2*7)+(1*2)=204
204 % 10 = 4
So 948048-72-4 is a valid CAS Registry Number.
948048-72-4Relevant articles and documents
C(sp3) -C(sp2) Method for constructing key and β - aryl amino acid preparation method
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Paragraph 0051; 0057-0059; 0061, (2021/10/27)
The invention provides C. (sp3) - C(sp2) A method for constructing a key and β -aryl amino acid relates to the technical field of chemical substance synthesis and transition metal application, which comprises β-C amino acid. (sp3) Ring carbon C in place of phenolic hydroxyl group(sp2) A method of constructing C-C keys by direct coupling. The process will contain inactive β-C. (sp3) Amino acids of - H and ligands L of specific structure1 The tetradentate chelate is generated by complexation with bivalent nickel, and the amino acid labile β-C is completed under the catalysis of palladium with phenolic ester under basic conditions. (sp3) - H Aryl, proton transfer and the like are reacted to achieve C. (sp3) - C(sp2) Construction of a bond, finally hydrolytically releasing β-C aryl amino acid and ligand L1 C. (sp3) - C(sp2) The key construction method is simple and convenient to operate. The method has the advantages of low cost, strong reaction universality, high yield and stereoselectivity. The synthetic method provides a novel method for preparing various non-natural β - aryl amino acids, and provides a novel method for amino acidification/peptide modification of phenolic compounds with biological activity, and provides a novel approach and selection for the design and synthesis of new drugs.
