94839-55-1

Basic information

• Product Name: Trisulfide, methyl phenylmethyl
• CAS NO: 94839-55-1
• Molecular Formula: C8H10S3
• Molecular Weight: 202.365
• Mol File: 94839-55-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Trisulfide, methyl phenylmethyl(CAS DataBase Reference)
• NIST Chemistry Reference: Trisulfide, methyl phenylmethyl(94839-55-1)
• EPA Substance Registry System: Trisulfide, methyl phenylmethyl(94839-55-1)

Safety Data

• Hazardous Substances Data: 94839-55-1(Hazardous Substances Data)

Upstream product

• 150-60-7 dibenzyl disulphide 
• 2949-92-0 methanethiosulfonic acid S-methyl ester 
• 94839-60-8 Methoxycarbonylmethyl trisulfane 
• 100-53-8 phenylmethanethiol 
• 74-93-1 methylthiol 
• 5797-02-4 acetyl benzyl disulfide 

Relevant articles and documents

An Esterase-Sensitive Prodrug Approach for Controllable Delivery of Persulfide Species

A strategy to deliver a well-defined persulfide species in a biological medium is described. Under near physiological conditions, the persulfide prodrug can be activated by an esterase to generate a “hydroxymethyl persulfide” intermediate, which rapidly collapses to form a defined persulfide. Such persulfide prodrugs can be used either as chemical tools to study persulfide chemistry and biology or for future development as H2S-based therapeutic reagents. Using the persulfide prodrugs developed in this study, the reactivity between S-methyl methanethiosulfonate (MMTS) with persulfide was unambiguously demonstrated. Furthermore, a representative prodrug exhibited potent cardioprotective effects in a murine model of myocardial ischemia-reperfusion (MI/R) injury with a bell shape therapeutic profile.