94871-48-4Relevant articles and documents
An Efficient Synthesis of 1,3-Diphenyl-3-phenylamino-propan-1-one and its Derivatives by Mannich Reaction in the Presence of Doped Porous Carbon by Nitrogen and Sulfur (NS-PCS) as Catalyst
Mansoori, Aida,Eshghi, Hossein,Lari, Jalil
, p. 548 - 553 (2017/12/28)
Synthesis of β-amino carbonyl compounds by Mannich reaction involves the creation of various bonds in a single action and is attracting great attention as one of the most powerful synthetic tools for the expansion of molecular convolution and versatility. Carbon spheres (CSs) combine the advantages of carbon materials with spherical colloids, which gives them several inimitable features as catalysts. In this work, the reaction between acetophenone, aromatic aldehydes, and aromatic amines has been efficiently catalyzed by porous carbon spheres which were doped by nitrogen and sulfur (NS-PCS) at ambient temperature to give diverse β-amino carbonyl compounds in nearly high yields.
Ionic amino acids: Application as organocatalysts in the aza-Michael reaction
Morimoto, Naoki,Takeuchi, Yasuo,Nishina, Yuta
, p. 31 - 37 (2013/04/10)
The ethyl methyl imidazolium salts of amino acids, [emim][AA], have been used as catalysts in the aza-Michael reaction. Furthermore, when chiral amino acids were used, a stereoselective reaction was achieved. The mechanism of the transformation was verified by the detection of a key intermediate by electrospray ionization mass spectroscopy (ESI-MS).
Novel one-pot Cu-nanoparticles-catalyzed Mannich reaction
Kidwai, Mazaahir,Mishra, Neeraj Kumar,Bansal, Vikas,Kumar, Ajeet,Mozumdar, Subho
body text, p. 1355 - 1358 (2009/06/28)
Recyclable heterogeneous Cu-nanoparticles efficiently catalyzed the one-pot three-component Mannich reaction of ketones, aromatic aldehydes and amines in methanol. This method provides a novel and improved method for obtaining β-amino carbonyl compounds in terms of good yield with little catalyst loading.
