949168-34-7

Basic information

• Product Name: methyl 2-(2-bromo-4-fluorophenyl) acetate
• Synonyms: methyl 2-(2-bromo-4-fluorophenyl) acetate
• CAS NO: 949168-34-7
• Molecular Weight: 247.064
• Mol File: 949168-34-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-bromo-4-fluorophenyl) acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-bromo-4-fluorophenyl) acetate(949168-34-7)
• EPA Substance Registry System: methyl 2-(2-bromo-4-fluorophenyl) acetate(949168-34-7)

Safety Data

• Hazardous Substances Data: 949168-34-7(Hazardous Substances Data)

Upstream product

• 61150-57-0 2-bromo-4-fluorobenzyl bromide 
• 61150-58-1 2-(2-bromo-4-fluorophenyl)acetonitrile 

Downstream Products

• 1340079-04-0 2-(2-bromo-4-fluorophenyl)acetaldehyde 
• 59142-68-6 2-bromo-4-fluorobenzaldehyde 
• 1566583-97-8 2-(4-fluoro-2-(2-(2-((4-(piperidin-4-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)phenyl)acetamide 
• 1566584-72-2 tert-butyl 4-(4-((4-(2-(2-amino-2-oxoethyl)-5-fluorophenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperidine-1-carboxylate 
• 1566584-71-1 lithium 2-(2-(2-(2-((4-(1-(tert-butoxycarbonyl)piperidin-4-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)-4-fluorophenyl)acetate 

Relevant articles and documents

Chiral Magnesium Bisphosphate-Catalyzed Asymmetric Double C(sp3)-H Bond Functionalization Based on Sequential Hydride Shift/Cyclization Process

Described herein is a chiral magnesium bisphosphate-catalyzed asymmetric double C(sp3)-H bond functionalization triggered by a sequential hydride shift/cyclization process. This reaction consists of stereoselective domino C(sp3)-H bond functionalization: (1) a highly enantio- and diastereoselective C(sp3)-H bond functionalization by chiral magnesium bisphosphate (first [1,5]-hydride shift), and (2) a highly diastereoselective C(sp3)-H bond functionalization by an achiral catalyst (Yb(OTf)3, second [1,5]-hydride shift).