94938-02-0

Basic information

• Product Name: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE
• Synonyms: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE;1-methyl-2-phenyl-1H-imidazole-4-carboxaldehyde
• CAS NO: 94938-02-0
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.2099
• Mol File: 94938-02-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE(94938-02-0)
• EPA Substance Registry System: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE(94938-02-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 94938-02-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 29, p. 261, 1986 DOI: 10.1021/jm00152a015

Upstream product

• 100-47-0 benzonitrile 
• 68282-47-3 2-phenyl-1H-imidazole-4-carbaldehyde 
• 74-88-4 methyl iodide 
• 616-38-6 carbonic acid dimethyl ester 
• 77-78-1 dimethyl sulfate 
• 99280-78-1 (1-methyl-2-phenyl-1H-imidazol-4-yl)methanol 
• 43002-54-6 (2-phenyl-1H-imidazol-4-yl)-methanol 

Downstream Products

• 851182-98-4 bis[(1-methyl-2-phenyl-4-imidazolyl)methyl]amine 
• 851182-97-3 bis[(1-methyl-2-phenyl-4-imidazolyl)methyl]benzylamine 

Relevant articles and documents

Copper-catalyzed intramolecular dehydrogenative aminooxygenation: Direct access to formyl-substituted aromatic N-heterocycles

A direct synthesis of carbaldehydes through intramolecular dehydrogenative aminooxygenation has been developed. The process uses a catalytic amount of copper(II) in DMF or DMA under oxygen and does not require additional oxidants (see scheme). Mechanistic studies suggest that the carbonyl oxygen atom of the aldehyde is derived from oxygen through a copper-mediated oxygen activation process via a peroxy-copper(III) intermediate. Copyright

Synthesis and reactivity of a (μ-1,1-hydroperoxo)(μ-hydroxo) dicopper(II) complex: Ligand hydroxylation by a bridging hydroperoxo ligand

A new tetradentate tripodal ligand (L3) containing sterically bulky imidazolyl groups was synthesized, where L3 is tris(1-methyl-2-phenyl-4- imidazolylmethyl)amine. Reaction of a bis(μ-hydroxo)dicopper(II) complex, [Cu2(L3)2(OH)

Cardiotonic agents. 3. Synthesis and biological activity of novel 6-(substituted 1H-imidazol-4(5)-yl)-3(2H)-pyridazinones

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