94956-98-6

Basic information

• Product Name: 2-allyl-3-methoxybenzaldehyde
• Synonyms: 2-allyl-3-methoxybenzaldehyde
• CAS NO: 94956-98-6
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 176.21178
• Product Categories: Treprostinil
• Mol File: 94956-98-6.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 269.6±25.0 °C(Predicted)
• Appearance: /
• Density: 1.039±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-allyl-3-methoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-allyl-3-methoxybenzaldehyde(94956-98-6)
• EPA Substance Registry System: 2-allyl-3-methoxybenzaldehyde(94956-98-6)

Safety Data

• Hazardous Substances Data: 94956-98-6(Hazardous Substances Data)

Usage

General Description

2-Allyl-3-methoxybenzaldehyde is an organic compound with the molecular formula C11H12O2. It is a member of the benzaldehyde family and possesses a methoxy group at the 3 position and an allyl group at the 2 position on the aromatic ring. The structure is notable for the presence of an aromatic ring, a carbonyl group, and an unsaturated carbon chain. The compound is noted for its pleasant aroma and has been detected in plant and food extracts, including clove oil. It has potential usage in natural product synthesis and pharmaceuticals because of its potential biological activity.

Upstream product

• 106-95-6 allyl bromide 
• 79950-42-8 2-allyl-3-hydroxy-benzaldehyde 
• 77-78-1 dimethyl sulfate 
• 1613271-10-5 2-allyl-3-methoxybenzyl 3,5-dinitrobenzoate 
• 74-83-9 methyl bromide 
• 591-31-1 3-methoxy-benzaldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 40359-32-8 3-allyloxy-benzaldehyde 
• 136911-16-5 (2-allyl-3-methoxyphenyl)methanol 
• 223734-55-2 2-allyl-3-methoxy-O-tert-butyldimethylsilylbenzyl alcohol 
• 153974-48-2 3-methoxy-O-tert-butyldimethylsilylbenzyl alcohol 
• 6971-51-3 3-methoxybenzyl alcohol 

Downstream Products

• 90806-58-9 5-methoxyisoquinoline 
• 1390647-77-4 9,10-dichloro-4-methoxy-6-methyl-5,6-dihydro-benzo[4,5]imidazo[2,1-a]isoquinoline 
• 1390647-91-2 4-methoxy-6-methyl-5,6-dihydro-6a,10,11-triaza-benzo[a]fluorene 
• 1390647-90-1 4-methoxy-6-methyl-5,6-dihydro-6a,9,11-triaza-benzo[a]fluorene 
• 1390647-89-8 4-methoxy-6-methyl-5,6-dihydro-6a,13-diaza-dibenzo[a,h]fluorene 
• 1390647-83-2 4-methoxy-6,9,10-trimethyl-5,6-dihydro-benzo[4,5]imidazo[2,1-a]isoquinoline 
• 1390647-71-8 4-methoxy-6-methyl-5,6-dihydro-benzo[4,5]imidazo[2,1-a]isoquinoline 
• 91344-50-2 8-methoxy-naphthalen-2-ol 
• 1613271-12-7 (R)-1-(2-allyl-3-methoxyphenyl)-6,7-bis((tert-butyldimethylsilyl)oxy)hept-2-yn-1-one 
• 1613271-13-8 (1S,6R)-1-(2-allyl-3-methoxyphenyl)-6,7-bis((tert-butyldimethylsilyl)oxy)hept-2-yn-1-ol 
• 1613271-14-9 (5S,10R)-5-(2-allyl-3-methoxyphenyl)-10-((tert-butyldimethylsilyl)oxy)-2,2,3,3,13,13,14,14-octamethyl-4,12-dioxa-3,13-disilapentadec-6-yne 

Relevant articles and documents

Nickel-Catalyzed Intramolecular Hydroalkenylation of Imines

A ligand-enabled nickel-catalyzed intramolecular hydroalkenylation of imines with unactivated alkenes has been developed. A variety of five- and six-membered cyclic allylic amines were synthesized in high yields. The use of both wide-bite-angle diphosphine ligand and Br?nsted acid is crucial for realizing the reaction. Preliminary investigation of the asymmetric intramolecular hydroalkenylation of imines shows promising potential for the application of the method in the synthesis of enantio-enriched cyclic allylic amines.

PdCl2/CuCl2/Bi(OTf)3-promoted Construction of Sulfonyl Dibenzooxabicyclo[3.3.1]nonanes and Arylnaphthalenes via Intramolecular Annulation of Sulfonyl o-Allylarylchromanones

PdCl2/CuCl2/Bi(OTf)3-promoted intramolecular domino annulation of sulfonyl o-allylarylchromanones provides tetracyclic sulfonyl dibenzooxabicyclo[3.3.1]nonanes and bicyclic arylnaphthalenes with good to excellent yields in MeOH at room (25 °C) and refluxing (65 °C) temperature, respectively. The starting sulfonyl o-allylarylchromanones can be easily obtained from the intermolecular cyclocondensation of α-sulfonyl o-hydroxyacetophenones and o-allylbenzaldehydes. The uses of various catalysts and solvent systems are investigated herein for convenient transformation. A plausible mechanism is proposed and discussed. This protocol provides one-pot ring closure via carbon-carbon (C?C) bond formation. (Figure presented.).

Synthesis of Polysubstituted 3-Methylisoquinolines through the 6π-Electron Cyclization/Elimination of 1-Azatrienes derived from 1,1-Dimethylhydrazine

A convenient one pot microwave-assisted 6π-electron cyclization/aromatization approach toward 3-methylisoquinolines is reported. The starting 1-azatriene derivatives were prepared in situ by reaction of 2-propenylbenzaldehydes with 1,1-dimethylhydrazine, which exhibited superior performance when compared with other hydrazine derivatives. Minor amounts of the related 3,4-dihydro isoquinolines were formed concomitantly with the isoquinolines, and a mechanism for their generation was proposed. The reaction conditions were optimized, and its scope and limitations were explored. In general, the transformation proceeded in moderate to good yields.