949902-02-7

Basic information

• Product Name: 8-Benzyl-3-(trifluoroMethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene
• Synonyms: 8-Benzyl-3-(trifluoroMethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene;8-Benzyl-8-azabicyclo[3.2.1]oct-3-en-3-yl] trifluoromethanesulfonate
• CAS NO: 949902-02-7
• Molecular Formula: C₁₅H₁₆F₃NO₃S
• Molecular Weight: 347.3526496
• Mol File: 949902-02-7.mol
• Article Data: 5

Chemical Properties

• Appearance: Dark orange/Viscous Liquid, May Contain Suspension
• CAS DataBase Reference: 8-Benzyl-3-(trifluoroMethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Benzyl-3-(trifluoroMethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene(949902-02-7)
• EPA Substance Registry System: 8-Benzyl-3-(trifluoroMethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene(949902-02-7)

Safety Data

• Hazardous Substances Data: 949902-02-7(Hazardous Substances Data)

Upstream product

• 28957-72-4 N-benzyltropinone 
• 145100-51-2 N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 83393-23-1 N-8-benzyl[3.2.1]8-azabicyclooctan-3-one hydrochloride 

Downstream Products

• 949902-05-0 8-benzyl-3-(3-benzyloxyphenyl)-8-azabicyclo[3.2.1]oct-2-ene 
• 949902-22-1 3-(8-benzyl-8-azabicyclo[3.2.1]oct-2-en-3-yl)benzamide 
• 1211547-01-1 8-benzyl-3-(4-methoxy-phenyl)-8-aza-bicyclo[3.2.1]oct-2-ene 
• 1123661-57-3 3-(8-benzyl-8-aza-bicyclo[3.2.1]oct-2-en-3-yl)-2-tert-butoxy-benzonitrile 
• 1123661-15-3 8-benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-8-azabicyclo[3.2.1]oct-2-ene 

Relevant articles and documents

UREA DERIVATIVES OF SUBSTITUTED NORTROPANES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE

The present invention relates to compounds defined by formula I wherein the groups R1, Y1 to Y4, V, W, and X are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitor

Process for preparing an intermediate to opioid receptor antagonists

The invention provides an efficient method for preparing 3-endo-(8-azabicyclo[3.2.1]oct-3-yl)benzamide by hydrogenation, under controlled conditions, of an amino-protected 3-(8-azabicyclo[3.2.1 ]oct-2-en-3-yl)benzamide intermediate in which the amino-prot

8-Azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists

The invention provides novel 8-azabicyclo[3.2.1]octane compounds of formula (I): wherein R1, R2, R3, A, and G are defined in the specification, or a pharmaceutically-acceptable salt or solvate thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.