950984-75-5

Basic information

• Product Name: N,N-Bis(2-Pyridylmethyl)-N-Propargylamine
• Synonyms: N-propargyl-N,N-bis(2-pyridylmethyl)amine;N,N-Bis(2-Pyridylmethyl)-N-Propargylamine;N,N-bis(pyridin-2-ylmethyl)prop-2-yn-1-amine;(Prop-2-yn-1-yl)bis[(pyridin-2-yl)methyl]amine
• CAS NO: 950984-75-5
• Molecular Formula: C15H15N3
• Molecular Weight: 237.304
• Mol File: 950984-75-5.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: N,N-Bis(2-Pyridylmethyl)-N-Propargylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Bis(2-Pyridylmethyl)-N-Propargylamine(950984-75-5)
• EPA Substance Registry System: N,N-Bis(2-Pyridylmethyl)-N-Propargylamine(950984-75-5)

Safety Data

• Hazardous Substances Data: 950984-75-5(Hazardous Substances Data)

Upstream product

• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 2450-71-7 Propargylamine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 106-96-7 propargyl bromide 
• 4377-33-7 2-chloromethylpyridine 
• 119715-60-5 N-(2-pyridylmethyl)-2-pyridylmethanimine 
• 1539-42-0 bis[(2-pyridyl)methyl]amine 

Downstream Products

• 1192206-14-6 C₂₂H₂₂N₆O 
• 1567833-49-1 C₇₅H₁₀₂N₂₄O₁₃S 
• 1546975-40-9 1-(3-phenylisoxazol-5-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine 

Relevant articles and documents

Synthesis of DPA-triazole structures and their application as ligand for metal catalyzed organic reactions

In this work, the use of DPA-triazole (DPA = dipicolylamine) molecules as ligands for metal catalyzed organic reactions has been investigated. A small library of ligands has been prepared by a CuAAC (click reaction) between propargyl-DPA and different azi

Molecular Recognition by Zn(II)-Capped Dynamic Foldamers

Two α-aminoisobutyric acid (Aib) foldamers bearing Zn(II)-chelating N-termini have been synthesized and compared with a reported Aib foldamer that has a bis(quinolinyl)/mono(pyridyl) cap (BQPA group). Replacement of the quinolinyl arms of the BQPA-capped foldamer with pyridyl gave a BPPA-capped foldamer, then further replacement of the linking pyridyl with a 1,2,3-triazole gave a BPTA-capped foldamer. Their ability to relay chiral information from carboxylate bound to Zn(II) at the N-terminus to a glycinamide-based NMR reporter of conformational preference at the C-terminus was measured. The importance of the quinolinyl arms became readily apparent, as the foldamers with pyridyl arms were unable to report on the presence of chiral carboxylate in acetonitrile. Low solubility, X-ray crystallography and 1H NMR spectroscopy suggested that interfoldamer interactions inhibited carboxylate binding. However changing solvent to methanol revealed that the end-to-end relay of chiral information could be observed for the Zn(II) complex of the BPTA-capped foldamer at low temperature.

An alternative modular 'click-SNAr-click' approach to develop subcellular localised fluorescent probes to image mobile Zn2+

Zn2+ is involved in a number of biological processes and its wide-ranging roles at the subcellular level, especially in specific organelles, have not yet been fully established due to a lack of tools to image it effectively. We report a new and