951626-52-1

Basic information

• Product Name: ethyl 2-(4-fluorophenyl)-1H-imidazole-5-carboxylate
• CAS NO: 951626-52-1
• Molecular Weight: 234.23
• Mol File: 951626-52-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-(4-fluorophenyl)-1H-imidazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-fluorophenyl)-1H-imidazole-5-carboxylate(951626-52-1)
• EPA Substance Registry System: ethyl 2-(4-fluorophenyl)-1H-imidazole-5-carboxylate(951626-52-1)

Safety Data

• Hazardous Substances Data: 951626-52-1(Hazardous Substances Data)

Upstream product

• 403-43-0 4-fluorobenzoyl chloride 
• 366-79-0 p-fluorohippuric Acid 
• 623-49-4 ethyl cyanoformate 
• 105669-21-4 2-(4-Fluorphenyl)-4,5-dihydro-1,3-oxazol-5-on 

Relevant articles and documents

Synthesis of di- and tri-substituted imidazole-4-carboxylates via PBu3-mediated [3+2] cycloaddition

Some new di- and trisubstituted imidazole-4-carboxylates were prepared from amidoacetic acids 3 in the present report. The key step to establish such imidazole- 4-carboxylates stemmed from the PBu3-mediated [3+2] cycloaddition between in situ-generated Δ2-oxazolinone 4 and ethyl cyanoformate6. Our results indicated that trisubstituted imidazoles 7-20 were afforded in better yields than those of disubstituted imidazoles 21-27. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications1 to view the free supplemental file. Copyright Taylor & Francis Group, LLC.