951631-04-2Relevant articles and documents
Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists
Chen, Mi,Guo, Zhiqiang,Lanier, Marion C.,Zhao, Liren,Betz, Stephen F.,Huang, Charles Q.,Loweth, Colin J.,Ashweek, Neil J.,Liu, Xin-Jun,Struthers, R. Scott,Bradbury, Margaret J.,Behan, James W.,Wen, Jenny,O'Brien, Zhihong,Saunders, John,Zhu, Yun-Fei
, p. 3845 - 3850 (2008/02/13)
A novel series of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives were designed and synthesized as GnRH receptor antagonists. SAR studies led to a series of highly active molecules against both the rat and human receptors. Furt
