952182-18-2 Usage
Description
METHYL 5-AMINO-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLATE, also known as 5-Amino-1H-pyrrolo[2,3-b]pyridine-2-carboxylic Acid Methyl Ester, is an organic compound that serves as a reagent in the synthesis of various chemical compounds. It is characterized by its unique molecular structure, which includes a pyrrolo[2,3-b]pyridine core and a carboxylic acid group esterified with a methyl group.
Uses
Used in Pharmaceutical Industry:
METHYL 5-AMINO-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLATE is used as a reagent for the synthesis of azaindole derivatives, which are dual inhibitors of Alb and Src kinases. These azaindole derivatives have potential applications in the development of novel therapeutic agents for the treatment of various diseases, including cancer and inflammatory disorders.
In the pharmaceutical industry, the compound plays a crucial role in the discovery and development of new drugs targeting specific kinases, which are enzymes that play a key role in cellular signaling pathways. By inhibiting the activity of Alb and Src kinases, these azaindole derivatives can potentially modulate cellular processes and pathways involved in disease progression, offering new treatment options for patients.
Furthermore, the use of METHYL 5-AMINO-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLATE in the synthesis of azaindole derivatives highlights its importance as a building block in medicinal chemistry. Its unique structure and reactivity make it a valuable tool for chemists and researchers working on the design and synthesis of new bioactive compounds with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 952182-18-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,2,1,8 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 952182-18:
(8*9)+(7*5)+(6*2)+(5*1)+(4*8)+(3*2)+(2*1)+(1*8)=172
172 % 10 = 2
So 952182-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3O2/c1-14-9(13)7-3-5-2-6(10)4-11-8(5)12-7/h2-4H,10H2,1H3,(H,11,12)
952182-18-2Relevant articles and documents
PROTEIN KINASE INHIBITORS
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Page/Page column 41, (2014/07/21)
The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus also includes the preparation of compounds of formula (I), their uses, in particular in the inhibition of protein kinases which are implicated for example in numerous diseases such as cancers or immune system disorders.
NOVEL CC-1065 ANALOGS AND THEIR CONJUGATES
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Page/Page column 148, (2010/06/17)
This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
