95237-08-4Relevant articles and documents
Favourable involvement of α2A-adrenoreceptor antagonism in the I2-imidazoline binding sites-mediated morphine analgesia enhancement
Mammoli, Valerio,Bonifazi, Alessandro,Del Bello, Fabio,Diamanti, Eleonora,Giannella, Mario,Hudson, Alan L.,Mattioli, Laura,Perfumi, Marina,Piergentili, Alessandro,Quaglia, Wilma,Titomanlio, Federica,Pigini, Maria
, p. 2259 - 2265 (2012/05/05)
Aim of the present study was to obtain novel α2- adrenoreceptor (α2-AR) antagonists, possibly endowed with subtype-selectivity. Therefore, inspired by the non subtype-selective α2-AR antagonist idazoxan, we designed 1,4-di