952489-10-0

Basic information

• Product Name: methyl (9S)-3-(acetyloxy)-9-{formyl[(1R)-1-phenylethyl]amino}-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate
• Synonyms: methyl (9S)-3-(acetyloxy)-9-{formyl[(1R)-1-phenylethyl]amino}-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate
• CAS NO: 952489-10-0
• Molecular Weight: 413.43
• Mol File: 952489-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (9S)-3-(acetyloxy)-9-{formyl[(1R)-1-phenylethyl]amino}-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (9S)-3-(acetyloxy)-9-{formyl[(1R)-1-phenylethyl]amino}-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate(952489-10-0)
• EPA Substance Registry System: methyl (9S)-3-(acetyloxy)-9-{formyl[(1R)-1-phenylethyl]amino}-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate(952489-10-0)

Safety Data

• Hazardous Substances Data: 952489-10-0(Hazardous Substances Data)

Upstream product

• 128173-50-2 O-Benzyl-N-(tert-butoxycarbonyl)-N-(4-cyanobutyl)-hydroxylamine 
• 6280-87-1 δ-chlorovaleronitrile 
• 724445-24-3 methyl 3-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate 
• 724445-29-8 methyl-3-(benzyloxy)-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate 
• 724445-33-4 methyl 3-(benzoyloxy)-9-bromo-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate 
• 724445-31-2 methyl 3-(benzoyloxy)-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate 
• 724445-22-1 methyl 2-(2-methoxy-2-oxoethyl)-5,6,7,8-tetrahydro-2H-[1,2,4]oxadiazolo[2,3-a]pyridine-2-carboxylate 
• 108-24-7 acetic anhydride 

Relevant articles and documents

The synthesis of tetrahydropyridopyrimidones as a new scaffold for HIV-1 integrase inhibitors

An efficient synthesis of methyl 9-amino-3-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate as a late stage intermediate for a new class of HIV-1 integrase inhibitors is described. After construction of the bicyclic core scaffold,