953039-65-1 Usage
Description
7-Bromoquinazolin-2(1H)-one, also known as 2(1H)-Quinazolinone, 7-bromo-, is a white to off-white solid chemical compound commonly used in pharmaceutical and chemical research. It is a derivative of quinazolinone and possesses potential pharmacological properties, including anti-inflammatory, antitumor, and anti-cancer activities. With a molecular formula of C8H5BrN2O and a molecular weight of 219.04 g/mol, 7-BROMOQUINAZOLIN-2(1H)-ONE is known for its diverse biological activities and is often used as a building block in the synthesis of various compounds for medicinal chemistry research. It is important to handle this chemical with caution and in accordance with proper safety procedures due to its potential hazards.
Uses
Used in Pharmaceutical Research:
7-BROMOQUINAZOLIN-2(1H)-ONE is used as a building block for the synthesis of various compounds in pharmaceutical research for its potential pharmacological properties, including anti-inflammatory, antitumor, and anti-cancer activities.
Used in Medicinal Chemistry Research:
7-BROMOQUINAZOLIN-2(1H)-ONE is used as a key intermediate in the development of new drugs and therapeutic agents in medicinal chemistry research, leveraging its diverse biological activities and potential pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 953039-65-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,3,0,3 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 953039-65:
(8*9)+(7*5)+(6*3)+(5*0)+(4*3)+(3*9)+(2*6)+(1*5)=181
181 % 10 = 1
So 953039-65-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2O/c9-6-2-1-5-4-10-8(12)11-7(5)3-6/h1-4H,(H,10,11,12)
953039-65-1Relevant articles and documents
NOVEL 6-6 BICYCLIC AROMATIC RING SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS
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Page/Page column 258, (2017/03/14)
The present invention relates novel 6-6 bicyclic aromatic ring substituted nucleoside analogues of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
QUINAZOLINES FOR PDK1 INHIBITION
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, (2008/06/13)
The invention provides novel quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
