953395-36-3

Basic information

• Product Name: (+/-)-4-(2-(4-methylphenylsulfonamido)phenyl)-2-butyl 2-ethynylbenzoate
• Synonyms: (+/-)-4-(2-(4-methylphenylsulfonamido)phenyl)-2-butyl 2-ethynylbenzoate
• CAS NO: 953395-36-3
• Molecular Weight: 447.555
• Mol File: 953395-36-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-4-(2-(4-methylphenylsulfonamido)phenyl)-2-butyl 2-ethynylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-4-(2-(4-methylphenylsulfonamido)phenyl)-2-butyl 2-ethynylbenzoate(953395-36-3)
• EPA Substance Registry System: (+/-)-4-(2-(4-methylphenylsulfonamido)phenyl)-2-butyl 2-ethynylbenzoate(953395-36-3)

Safety Data

• Hazardous Substances Data: 953395-36-3(Hazardous Substances Data)

Upstream product

• 457622-20-7 4-(2-aminophenyl)-2-butanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 953395-33-0 C₁₇H₂₁NO₃S 
• 33578-00-6 (2-ethynyl)benzoic acid 

Downstream Products

• 49849-64-1 1-(4-methylbenzenesulfonyl)-2-methyl-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

Catalytic activation of the leaving group in the SN2 reaction

A novel catalytic activation of the leaving group in the SN2 reaction is achieved as an extension of our mercuric triflate-catalyzed reactions. Derivatives of anilinoethyl 4-pentynoate reacted smoothly with catalytic amounts of Hg(OTf)2 to give indoline derivatives in excellent yield with efficient catalytic turnovers under very mild conditions. The reaction of optically pure secondary alcohol derivatives resulted in inversion of stereochemistry, which is a definitive feature of the S N2 reaction. The procedure is applicable for benzoazepine synthesis.