95351-73-8

Basic information

• Product Name: 2-Propene-1-thiol, 3-phenyl-, (E)-
• CAS NO: 95351-73-8
• Molecular Formula: C9H10S
• Molecular Weight: 150.244
• Mol File: 95351-73-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Propene-1-thiol, 3-phenyl-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propene-1-thiol, 3-phenyl-, (E)-(95351-73-8)
• EPA Substance Registry System: 2-Propene-1-thiol, 3-phenyl-, (E)-(95351-73-8)

Safety Data

• Hazardous Substances Data: 95351-73-8(Hazardous Substances Data)

Usage

Also known as

(E)-3-phenyl-2-propenethiol

Physical state

Liquid

Color

Colorless to pale yellow

Odor

Strong, unpleasant

Uses

Flavoring agent in the food industry, intermediate in pharmaceutical and agrochemical production, synthesis of heterocyclic compounds, research tool in organic chemistry

Potential hazards

Irritation to skin, eyes, and respiratory system.

Upstream product

• 64931-96-0 2-[(E)-cinnamyl]thiouronium bromide 
• 226090-89-7 S-[(2E)-3-phenylprop-2-en-1-yl]ethanthioate 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 4392-24-9 Cinnamyl bromide 

Downstream Products

• 85022-06-6 [(E)-3-(1,2,2,2-Tetrachloro-ethylsulfanyl)-propenyl]-benzene 
• 1579955-76-2 S-cinnamyl 2-cyanoethanethioate 
• 79636-76-3 ((E)-2,3-Dichloro-1-vinyl-allyl)-benzene 
• 79636-54-7 [(E)-3-(2,2-Dichloro-vinylsulfanyl)-propenyl]-benzene 
• 119785-34-1 <1α,2α(Z),3α(E),4α>-(+/-)-7-<3-<<(3-Phenyl-2-propenyl)thio>methyl>-7-oxabicyclo<2.2.1>hept-2-yl>-5-heptenoic acid 

Relevant articles and documents

Direct synthesis of thiols from halides and epoxides using hydrosulfide exchange resin in methanol

Various thiols are prepared directly from the corresponding alkyl halides and epoxides using hydrosulfide exchange resin in methanol in the presence of equimolar amounts of triethylammonium chloride at room temperature. The reaction not only proceeds with unique chemoselectivity, but also gives better yields of thiols than most commonly used indirect methods and has an additional advantage of a simple workup.

Highly enantioselective reactions of a lithiated α-thioallyl carbanion via thermodynamic resolution pathway

S-Cinnamyl thiocarbamate 9, easily accessible from cinnamyl alcohol, undergoes smooth deprotonation with n-BuLi in the presence of various chiral ligands to form configurationally unstable organolithium intemediates. With the proper choice of chiral ligand, the diastereomeric equilibrium is almost fully shifted to one side, furnishing highly enantioenriched products after reaction with various electrophiles.

6-O-acyl ketolide antibacterials

6-O-Acyl ketolide antibacterials of the formula: wherein R1, R2, R3, R4, W, X, X′, Y, and Y′ are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.