95413-30-2

Basic information

• Product Name: Methanesulfonic acid (R)-2-methyl-4-oxo-3-(2-propynyl)-2-cyclopentenyl ester
• Synonyms: (R)-3-Methyl-4-[(methylsulfonyl)oxy]-2-(2-propynyl)-2-cyclopenten-1-one;Methanesulfonic acid (R)-2-methyl-4-oxo-3-(2-propynyl)-2-cyclopentenyl ester
• CAS NO: 95413-30-2
• Molecular Formula: C₁₀H₁₂O₄S
• Molecular Weight: 0
• Mol File: 95413-30-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methanesulfonic acid (R)-2-methyl-4-oxo-3-(2-propynyl)-2-cyclopentenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid (R)-2-methyl-4-oxo-3-(2-propynyl)-2-cyclopentenyl ester(95413-30-2)
• EPA Substance Registry System: Methanesulfonic acid (R)-2-methyl-4-oxo-3-(2-propynyl)-2-cyclopentenyl ester(95413-30-2)

Safety Data

• Hazardous Substances Data: 95413-30-2(Hazardous Substances Data)

Upstream product

• 94412-95-0 (R)-2-methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl nitrate 
• 90428-87-8 (S)-4-acetoxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 
• 96189-00-3 (+/-)-4-acetoxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 
• 139107-32-7 C₉H₁₁BO₄ 
• 77832-42-9 (R)-4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 77087-34-4 (S)-4-hydroxy-3-methyl-2-(2-propynyl)-cyclopent-2-ene-1-one 
• 77832-42-9 (R)-4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 

Relevant articles and documents

Practical and Safe Sulfonylation of 2-Alkynyl and 2-Alkenyl Alcohols Using the Combined Bases of a Catalytic Amount of Tertiary Amine and Potassium Carbonate

Several 2-alkynyl and 2-alkenyl alcohols were effectively sulfonylated with methanesulfonyl chloride or p-toluenesulfonyl chloride using the combined bases of a catalytic amount of tertiary amine and potassium carbonate.The reaction was conducted with reliable safety and while avoiding the disposal of wasted amines.The mesylation of 2-propyn-1-ol proceeded on a large scale (more than 20 kg) without a substantial production of explosive 3-chloro-1-propyne.The choice of the catalysts was important, and sterically unhindered tertiary amines, such as trimethylamine, N,N-d imethylbenzylamine, and triethylamine, were effective.Without these catalysts the reactions were significantly retarded.The reaction was so mild that it could be applied to complex and optically active 4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one, which is an important alcohol moiety of synthetic pyrethroids.

PREPARATION OF OPTICALLY ACTIVE SECONDARY ALCOHOLS BY COMBINATION OF ENZYMATIC HYDROLYSIS AND CHEMICAL TRANSFORMATION

Several kinds of optically active secondary alcohols (S)-2, which are important intermediates of bioactive compounds, were prepared from the corresponding racemic acetate (+/-)-1 in high chemical and optical yields by combination of enzymatic hydrolysis and chemical transformation.