95436-24-1

Basic information

• Product Name: dimethyl 1-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxynaphthalene-2,3-dicarboxylate
• Synonyms: dimethyl 1-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxynaphthalene-2,3-dicarboxylate
• CAS NO: 95436-24-1
• Molecular Weight: 424.407
• Mol File: 95436-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl 1-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxynaphthalene-2,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 1-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxynaphthalene-2,3-dicarboxylate(95436-24-1)
• EPA Substance Registry System: dimethyl 1-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxynaphthalene-2,3-dicarboxylate(95436-24-1)

Safety Data

• Hazardous Substances Data: 95436-24-1(Hazardous Substances Data)

Upstream product

• 54370-00-2 2-bromo-4,5-dimethoxybenzyl alcohol 
• 52703-75-0 benzo[1,3]dioxol-5-yl-(6-formyl-3,4-dimethoxyphenyl)methanone 
• 2788-26-3 dimethyl 2-(dimethoxyphosphoryl)succinate 

Downstream Products

• 17951-19-8 justicidin B 
• 82001-16-9 4‐(benzo[d][1,3]dioxol‐5‐yl)‐6,7‐dimethoxynaphtho[2,3‐c]furan‐1(3H)‐one 
• 42923-60-4 2,3-bis-(hydroxymethyl)-6,7-methylenedioxy-1-(3',4'-dimethoxyphenyl)-naphthalene 
• 86431-57-4 2,3-bis-(hydroxymethyl)-6,7-dimethoxy-1-(3',4'-methylenedioxyphenyl)naphthalene 

Relevant articles and documents

A new benzannulation reaction and its application in the multiple parallel synthesis of arylnaphthalene lignans

A new aromatic annulation reaction based on sequential Horner-Emmons and Claisen condensation reactions is described. The method is high yielding and provides a rapid entry to arylnaphthalenes. The lignan natural products justicidin B 1, retrojusticidin B 2, taiwanin C 3, justicidin E 4, chinensin 5 and retrochinensin 6 have all been synthesised in good overall yield using this protocol, demonstrating its potential in multiple parallel synthesis. The selective oxidation of diols 34-36 to the corresponding retrolactones with barium manganate(VI) is also noteworthy.