95450-80-9Relevant articles and documents
Preparation method of anti-proliferation reactive intermediate ML-098
-
Paragraph 0011; 0020-0021, (2018/10/04)
The invention discloses a preparation method of an anti-proliferation reactive intermediate ML-098 with the chemical name of 1-(2-(2,5-dimethyl phenoxy)ethyl)-3-indolecarboxylic acid, and belongs to the field of a chemical medicine intermediate. The metho
Captodative olefins: Methyl 2-aryloxy-3-dimethyl-aminopropenoates and their application in a new synthesis of benzofurans
Cruz, María Del Carmen,Tamariz, Joaquín
, p. 2377 - 2380 (2007/10/03)
The β-substituted captodative olefins methyl 2-aryloxy-3- dimethylaminopropenoates 4a-h were synthesized, via aminomethylenation of the corresponding 2-phenoxyacetic esters 9a-h. Lewis acid promoted intramolecular cyclization of alkenes 4 led to benzofurans 7a-h, in an efficient synthetic approach to the benzofuran frame.