95458-69-8 Usage
Chemical structure
A hydrazone derivative of 2(3H)-oxazolone with a 4-phenyl substitution.
Type of compound
Cyclic organic compound.
Usage
Commonly used as an intermediate in organic synthesis.
Functional group
Hydrazone functional group.
Utility
Formation of hydrazones, which can be useful in the synthesis of pharmaceuticals, agrochemicals, and other bioactive compounds.
Investigation
Has been investigated for its potential use in various chemical reactions and as a building block for more complex organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 95458-69-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,4,5 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 95458-69:
(7*9)+(6*5)+(5*4)+(4*5)+(3*8)+(2*6)+(1*9)=178
178 % 10 = 8
So 95458-69-8 is a valid CAS Registry Number.
95458-69-8Relevant articles and documents
3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives: Inhibitors of immune complex induced inflammation
Haviv,Ratajczyk,DeNet,Kerdesky,Walters,Schmidt,Holms,Young,Carter
, p. 1719 - 1728 (2007/10/02)
3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives were evaluated in the dermal and pleural reverse passive Arthus reactions in the rat. In the pleural test these compounds were effective in reducing exudate volume and accumulation of white blood cells. This pattern of activity was similar to that of hydrocortisone and different from that of indomethacin. The structural requirements for inhibiting the Arthus reactions were studied by systematic chemical modification of 1. These structure-activity relationship studies revealed that nitrogen 1' of the hydrazino group is essential for activity and must be electron rich, whereas chemical modifications of other sites of 1 had only a modest effect on activity.
