95480-36-7

Basic information

• Product Name: 2-(3-acetylphenyl) propanoic acid
• Synonyms: 2-(3-acetylphenyl) propanoic acid
• CAS NO: 95480-36-7
• Molecular Weight: 192.214
• Mol File: 95480-36-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(3-acetylphenyl) propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-acetylphenyl) propanoic acid(95480-36-7)
• EPA Substance Registry System: 2-(3-acetylphenyl) propanoic acid(95480-36-7)

Safety Data

• Hazardous Substances Data: 95480-36-7(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 2510-99-8 ethyl 2-phenylpropanoate 
• 756501-87-8 2-(3-acetylphenyl)propanenitrile 
• 42872-29-7 3-(1-cyanoethyl)benzoyl chloride 
• 5537-71-3 2-(3-carboxyphenyl)propanenitrile 
• 124-38-9 carbon dioxide 
• 64217-99-8 1-(3-vinylphenyl)ethan-1-one 

Downstream Products

• 1397293-20-7 1-(3-(1-isocyanatoethyl)phenyl)ethanone 

Relevant articles and documents

Site-Selective Catalytic Carboxylation of Unsaturated Hydrocarbons with CO2 and Water

A catalytic protocol that reliably predicts and controls the site-selective incorporation of CO2 to a wide range of unsaturated hydrocarbons utilizing water as formal hydride source is described. This platform unlocks an opportunity to catalytically repurpose three abundant, orthogonal feedstocks under mild conditions.

Selective and potent urea inhibitors of cryptosporidium parvum inosine 5′-monophosphate dehydrogenase

Cryptosporidium parvum and related species are zoonotic intracellular parasites of the intestine. Cryptosporidium is a leading cause of diarrhea in small children around the world. Infection can cause severe pathology in children and immunocompromised patients. This waterborne parasite is resistant to common methods of water treatment and therefore a prominent threat to drinking and recreation water even in countries with strong water safety systems. The drugs currently used to combat these organisms are ineffective. Genomic analysis revealed that the parasite relies solely on inosine-5′-monophosphate dehydrogenase (IMPDH) for the biosynthesis of guanine nucleotides. Herein, we report a selective urea-based inhibitor of C. parvum IMPDH (CpIMPDH) identified by high-throughput screening. We performed a SAR study of these inhibitors with some analogues exhibiting high potency (IC50 1000-fold versus human IMPDH type 2 and good stability in mouse liver microsomes. A subset of inhibitors also displayed potent antiparasitic activity in a Toxoplasma gondii model.

Antiinflammatory and analgesic benzofuranoyl-phenylacetic acid derivatives

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