95540-90-2

Basic information

• Product Name: 1-Cyclohexyl-4,4,4-trifluoro-2-butyn-1-ol
• Synonyms: 1-Cyclohexyl-4,4,4-trifluoro-2-butyn-1-ol
• CAS NO: 95540-90-2
• Molecular Weight: 206.208
• Mol File: 95540-90-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Cyclohexyl-4,4,4-trifluoro-2-butyn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclohexyl-4,4,4-trifluoro-2-butyn-1-ol(95540-90-2)
• EPA Substance Registry System: 1-Cyclohexyl-4,4,4-trifluoro-2-butyn-1-ol(95540-90-2)

Safety Data

• Hazardous Substances Data: 95540-90-2(Hazardous Substances Data)

Upstream product

• 661-54-1 3,3,3-trifluoroprop-1-yne 
• 53282-55-6 (trimethylsiloxymethylidene)cyclohexane 
• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 2043-61-0 cyclohexanecarbaldehyde 
• 943610-08-0 1,1-dichloro-3,3,3-trifluoro-2-tosyloxypropene 

Downstream Products

• 1147880-03-2 (E)-4-cyclohexyl-1,1,1-trifluoro-4-hydroxy-2-triethylsilyl-2-butene 
• 1211006-94-8 C₁₀H₁₂BrF₃ 
• 1241905-96-3 4-cyclohexyl-1,1,1-trifluoro-4-(p-toluenesulfonyloxy)but-2-yne 
• 1207376-70-2 (E)-1-cyclohexyl-4,4,4-trifluoro-2-buten-1-one 
• 1241906-14-8 3-cyclohexyl-3-(p-toluenesulfonyloxy)propan-2-one 
• 1241906-03-5 4-cyclohexyl-1,1,1-trifluoro-4-(p-toluenesulfonyloxy)buta-2,3-diene 
• 1241906-09-1 4-cyclohexyl-1,1,1-trifluoro-4-(p-toluenesulfonyloxy)butan-3-one 
• 1388860-20-5 (E)-1-cyclohexyl-2-(2,2,2-trifluoroethyl)but-2-en-1-one 
• 1388859-90-2 1-cyclohexyl-4,4,4-trifluorobut-2-yn-1-yl benzoate 
• 1388860-11-4 1-(benzoyloxy)-1-cyclohexyl-4,4,4-trifluorobutan-2-one 
• 1388859-75-3 1-cyclohexyl-4,4,4-trifluorobut-2-yn-1-yl ethanesulfonate 
• 1415348-35-4 1-allyloxy-1-cyclohexyl-4,4,4-trifluoro-2-butyne 

Relevant articles and documents

A novel synthesis of fluorine-containing cyclopentenones via Pauson-Khand reaction

Intermolecular Pauson-Khand reaction of fluoroalkylated alkynes with 2-norbornene or 2,5-norbornadiene at the reflux temperature of dichloroethane proceeded smoothly to give the corresponding cyclopentenone derivatives in high yields as a mixture of regio

2-Bromo-3,3,3-trifluoropropene: A facile trifluoromethylacetylene anion synthon

The introduction of trifluoromethylacetylene units into organic compounds has been further studied and extended. The direct reaction of two equivalents of Lithium Diisopropylamide with 2-bromo-3,3,3-trifluoropropene gave lithium trifluoromethylacetylide, the anion of which was trapped in greater than 90% overall yield with a variety of electrophiles.

NEW FLUORIDE ION-CATALYZED REACTION OF F-ALKYLACETYLENES WITH SILYL ENOL ETHERS. AN EFFICIENT ROUTE TO F-ALKYL-SUBSTITUTED PROPAPGYLIC ALCOHOLS AND α-HYDROXY KETONES

Treatment of F-alkylacetylenes, generated in situ from 1H-F-1-alkenephosphonates, with silyl enol ethers in the presence of a catalytic amount of tetrabutylammonium fluoride gives good yields of F-alkyl-substituted propargyl alcohols or 4-(1H-F-alkylidene)-1,3-dioxolane derivatives, the latter being converted to the corresponding α-hydroxy ketones.