95609-48-6

Basic information

• Product Name: 2(3H)-Furanone, 5-(3,4-dichlorophenyl)dihydro-
• Synonyms: 5-(3,4-dichlorophenyl)-dihydro-2(3H)-furanone;2(3H)-Furanone,5-(3,4-dichlorophenyl)dihydro
• CAS NO: 95609-48-6
• Molecular Formula: C10H8Cl2O2
• Molecular Weight: 231.078
• Mol File: 95609-48-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 64-65 °C
• Boiling Point: 384.8±42.0 °C(Predicted)
• Density: 1.406±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2(3H)-Furanone, 5-(3,4-dichlorophenyl)dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, 5-(3,4-dichlorophenyl)dihydro-(95609-48-6)
• EPA Substance Registry System: 2(3H)-Furanone, 5-(3,4-dichlorophenyl)dihydro-(95609-48-6)

Safety Data

• Hazardous Substances Data: 95609-48-6(Hazardous Substances Data)

Upstream product

• 95-50-1 1,2-dichloro-benzene 
• 2642-63-9 3',4'-dichloroacetophenone 
• 50597-19-8 3-(3,4-dichlorobenzoyl)-propionic acid 
• 118528-87-3 4-(3,4-dichlorophenyl)-4-hydroxybutanoic acid 

Downstream Products

• 79560-18-2 4-(3,4-dichlorophenyl)-4-phenylbutanoic acid 
• 79560-19-3 4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one 

Relevant articles and documents

Sertraline derivative and preparation method and application thereof

The invention discloses a sertraline derivative or a medicinal salt thereof. The structural general formula of the sertraline derivative is shown in the specification. The sertraline derivative has a good inhibition effect on cryptococcus neoformans, particularly, the compound D16 disclosed by the invention has a relatively good inhibition effect on candida glabrata 9073, candida tropicalis 10186, cryptococcus neoformans, candida albicans 5314, candida albicans 904, candida tropicalis 10186, drug-resistant candida albicans 103 and cryptococcus gottii.

Friedel-Crafts Synthesis of 4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone, a Key Intermediate in the Preparation of the Antidepressant Sertraline

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