95674-67-2

Basic information

• Product Name: diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate
• Synonyms: diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate
• CAS NO: 95674-67-2
• Molecular Weight: 492.535
• Mol File: 95674-67-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate(95674-67-2)
• EPA Substance Registry System: diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethenyl>benzoyl>-L-glutamate(95674-67-2)

Safety Data

• Hazardous Substances Data: 95674-67-2(Hazardous Substances Data)

Upstream product

• 1118-89-4 diethyl-L-glutamate hydrochloride 
• 95674-66-1 2,4-diamino-6-(4-carboxystyryl)-5-deazapteridine 
• 80360-04-9 2,4-Diamino-6-(carboxaldehyde)pyrido[2,3-d]pyrimidine 
• 70583-34-5 [4-((S)-1,3-Bis-ethoxycarbonyl-propylcarbamoyl)-benzyl]-triphenyl-phosphonium; bromide 

Downstream Products

• 95674-54-7 5,10-dideaza-5,6,7,8-tetrahydroaminopterin 
• 95674-53-6 5,10-dideazaaminopterin 
• 95693-79-1 diethyl N-<4-<2-(2,4-diamino-5-deaza-5,6,7,8-tetrahydro-6-pteridyl)ethyl>benzoyl>-L-glutamate 
• 95674-69-4 diethyl N-<4-<2-(2,4-diamino-5-deaza-6-pteridyl)ethyl>benzoyl>-L-glutamate 

Relevant articles and documents

Synthesis of the Antileucemic Agents 5,10-Dideazaaminopterin and 5,10-Dideaza-5,6,7,8-tetrahydroaminopterin

Total syntheses from pyridine precursors of 5,10-dideazaaminopterin (1) and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin (2) are described.These compounds exhibit significant in vivo activity against L1210 leukemia that comparable to that observed with meth