95676-73-6

Basic information

• Product Name: Carbamic acid, (5-bromo-2-pyridinyl)-, phenyl ester
• CAS NO: 95676-73-6
• Molecular Formula: C12H9BrN2O2
• Molecular Weight: 293.12
• Mol File: 95676-73-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (5-bromo-2-pyridinyl)-, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (5-bromo-2-pyridinyl)-, phenyl ester(95676-73-6)
• EPA Substance Registry System: Carbamic acid, (5-bromo-2-pyridinyl)-, phenyl ester(95676-73-6)

Safety Data

• Hazardous Substances Data: 95676-73-6(Hazardous Substances Data)

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
• 1885-14-9 phenyl chloroformate 
• 504-29-0 2-aminopyridine 

Relevant articles and documents

CYCLIC UREAS AS INHIBITORS OF ROCK

The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

Design and synthesis of novel antifungal triazole derivatives with good activity and water solubility

In order to find novel antifungal agents with good activity and aqueous solubility, a series of SYN-2869 analogues containing a pyridine ring were synthesized and evaluated for their in vitro antifungal activity and water solubility. The results indicated that some compounds showed potent activity against six pathogenic fungi. In particular, the analogue 17a having an isobutyl substitution on the triazolone exhibited significant broad spectrum antifungal activity. In addition, the water solubility of compound 17a was sufficiently improved over SYN-2869.