956901-22-7

Basic information

• Product Name: N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]methanesulfonamide
• Synonyms: N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]methanesulfonamide
• CAS NO: 956901-22-7
• Molecular Weight: 354.442
• Mol File: 956901-22-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]methanesulfonamide(956901-22-7)
• EPA Substance Registry System: N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]methanesulfonamide(956901-22-7)

Safety Data

• Hazardous Substances Data: 956901-22-7(Hazardous Substances Data)

Upstream product

• 1005172-60-0 C₁₃H₁₈F₂N₂O₃S₂ 
• 956901-21-6 N-(4-acetyl-2,6-difluorophenyl)methanesulfonamide 
• 886842-80-4 N-(4-bromo-2,6-difluorophenyl)methanesulfonamide 
• 67567-26-4 4-bromo-2,6-difluoroaniline 
• 196929-78-9 (R)-2-methylpropane-2-sulfinamide 

Downstream Products

• 958328-53-5 N-((1R)-1-{3,5-DIFLUORO-4-[(METHYLSULFONYL)AMINO]PHENYL}ETHYL)-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXAMIDE 
• 958328-83-1 7-TERT-BUTYL-N-((1R)-1-{3,5-DIFLUORO-4-[(METHYLSULFONYL)AMINO]PHENYL}ETHYL)-QUINOLINE-3-CARBOXAMIDE 
• 958328-95-5 N-((1R)-1-{3,5-DIFLUORO-4-[(METHYLSULFONYL)AMINO]PHENYL}ETHYL)-7-ISOPROPYL-QUINOLINE-3-CARBOXAMIDE 
• 958327-94-1 ((1R)-1-{3,5-difluoro-4-[(methylsulfonyl)amino]phenyl}ethyl)-6-(trifluoromethyl)quinoline-2-carboxamide 
• 956901-20-5 2-(6-tert-butylpyridin-3-yl)-N-((1R)-1-{3,5-difluoro-4-[(methylsulfonyl)amino]phenyl}ethyl)-2-methylcyclopropanecarboxamide 
• 1005174-25-3 N-{4-[(1R)-1-aminoethyl]-2,6-difluorophenyl}methanesulfonamide hydrochloride 
• 956901-23-8 N-{4-[(1R)-1-aminoethyl]-2,6-difluorophenyl}methanesulfonamide hydrochloride 

Relevant articles and documents

METHOD FOR PREPARING (R)-N-[4-(1-AMINO-ETHYL)-2,6-DIFLUORO-PHENYL]-METHANESULFONAMIDE

Disclosed in the present specification is a method capable of preparing N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]-methanesulfonamide (INT028-2) with high optical purity, through the selection of Ellman-chiral auxiliar

CYCLOPROPANECARBOXAMIDE COMPOUND

This invention relates to novel substituted N-(N-sulfonylaminoarylmethyl)cyclopropanecarboxamide compound and to their use in therapy. This invention provides 2-(6-tert-butylpyridin-3-yl)-N-((1R)-1-{3,5-difluoro-4-[(methylsulfonyl)amino]phenyl}ethyl)-2-me