95741-45-0

Basic information

• Product Name: Benzoic acid, 2,6-dimethyl-4-(phenylmethoxy)-
• CAS NO: 95741-45-0
• Molecular Formula: C16H16O3
• Molecular Weight: 256.301
• Mol File: 95741-45-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,6-dimethyl-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,6-dimethyl-4-(phenylmethoxy)-(95741-45-0)
• EPA Substance Registry System: Benzoic acid, 2,6-dimethyl-4-(phenylmethoxy)-(95741-45-0)

Safety Data

• Hazardous Substances Data: 95741-45-0(Hazardous Substances Data)

Upstream product

• 378185-88-7 tert-butyl(4-iodo-3,5-dimethylphenoxy)dimethylsilane 
• 80826-86-4 4-iodo-3,5-dimethylphenol 
• 28924-92-7 4-(benzyloxy)-2,6-dimethylbenzaldehyde 
• 70547-87-4 2,6-dimethyl-4-hydroxybenzaldehyde 
• 378185-89-8 4-(tert-butyldimethylsilanyloxy)-2,6-dimethylbenzaldehyde 

Downstream Products

• 75056-97-2 2,6-dimethyl-4-hydroxybenzoic acid 
• 164654-82-4 4-Benzyloxy-2,6-dimethylbenzoylchlorid 
• 306297-02-9 4-benzyloxy-2,6-dimethylbenzoic acid methyl ester 
• 81375-01-1 (4-Hydroxy-2,6-dimethylphenyl)phenylketon 
• 109467-96-1 2,6-dimethyl-4-benzyloxy-benzyl alcohol 
• 341035-38-9 (4-benzyloxy-2,6-dimethyl-phenyl)-acetonitrile 
• 101718-21-2 4-benzyloxy-2,6-dimethyl-benzoic acid dimethylamide 

Relevant articles and documents

New Acyloxymethyl Ketones: Useful Probes for Cysteine Protease Profiling

Peptidyl-acyloxymethyl ketones (AOMKs) belong to a class of selective, irreversible inhibitors (activity-based probes) widely used as chemical tools of investigating proteins, for example, in activity-based protein profiling. The synthesis of the AOMKs has always been challenging and current methodologies involve both solution and solid-phase synthesis. Herein, the synthesis of a new scaffold useful for the preparation of peptidyl-AOMKs is reported and it is demonstrated that the new synthetic probes bearing a 4-functionalized 2,6-dimethylbenzoate efficiently inhibit cysteine proteases like cathepsin B.