95789-30-3

Basic information

• Product Name: Cefotiamhexetil hydrochloride
• Synonyms: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester, dihydrochloride, (6R-(6-alpha,7-beta))-; 1-cyclohexyloxycarbonyloxyethyl (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-(2-dimethylaminoethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride; Cefotiam hexetil hydrochloride (JP14); Pansporin-T (TN); Pansporin-T; CTM-HE; SCE 2174; Cefotiam hexetil hydrochloride; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid,7-[[(2-amino-4-thiazolyl)- acetyl]amino]-3-[[[1-[2-(dimethylamino)- ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-,1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester,dihydrochloride,(6R,7R)-
• CAS NO: 95789-30-3
• Molecular Formula: C₂₇H₃₉Cl₂N₉O₇S₃
• Molecular Weight: 525.6281
• Mol File: 95789-30-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 980.8 °C at 760 mmHg
• Flash Point: 546.9 °C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Cefotiamhexetil hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cefotiamhexetil hydrochloride(95789-30-3)
• EPA Substance Registry System: Cefotiamhexetil hydrochloride(95789-30-3)

Safety Data

• Hazardous Substances Data: 95789-30-3(Hazardous Substances Data)

Usage

Description

Cefotiam hexetil hydrochloride is an orally active, broad-spectrum cephalosporin useful in the treatment of bacterial infections. It is a prodrug hydrolyzed in the GI tract and absorbed as cefotiam. Cefotiam hexetil hydrochloride is reported to be especially potent against Streptococci strains.

Chemical Properties

Off-White to Pale Yellow Solid

Uses

A semi-synthetic cephalosporin antibiotic. Antibacterial.

Definition

ChEBI: The dihydrochloride salt of cefotiam 1-(cyclohexyloxycarbonyloxy)ethyl ester. It is used as a prodrug for cefotiam.

Brand name

Pansporin T