95855-33-7Relevant articles and documents
Synthesis of Heterocyclic Compounds, XXXVIII. - Five-membered Heterocycles by Cyclization of 3-Benzoyl-4-oxobutanenitriles
Ciller, J. A.,Seoane, C.,Soto, J.L.
, p. 51 - 57 (2007/10/02)
A synthesis of N-benzylidene-2-furanamines 8 by means of cyanide addition to acylchalcones 2, followed by piperidine-catalyzed cyclization in the presence of an aldehyde is reported.The 2-pyrrolones 4 are formed together with the compounds 8.In the absence of an aldehyde no furan is obtained.The intermediate 2-aryl-3-benzoyl-4-oxo-4-phenylbutanenitriles 3are easily isolated.The N-benzylidene-2-furanamines 9 are obtained from the oxonitriles 5.