959392-22-4 Usage
Description
(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride, also known as Duloxetine EP Impurity F, is a chemical compound that is an impurity found in Duloxetine, an antidepressant medication. It is characterized by its unique molecular structure, which includes a naphthalene and thiophene ring connected to a propylamine group with a methyl group attached to the nitrogen atom. The hydrochloride salt form of this compound is typically used for its enhanced solubility and stability.
Uses
Used in Pharmaceutical Industry:
(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride is used as an impurity reference standard for the quality control and analysis of Duloxetine, an antidepressant medication. It helps ensure the purity and safety of the final drug product by providing a reference point for the detection and quantification of impurities during the manufacturing process.
Additionally, as an impurity of Duloxetine, it is important to study the pharmacokinetics and potential effects of this compound on the overall safety and efficacy of the medication. According to the provided materials, Duloxetine EP Impurity F exhibits linear pharmacokinetics in mice and is not associated with any drastic changes in blood pressure or heart rate, which is crucial information for the development and use of Duloxetine as a therapeutic agent.
Check Digit Verification of cas no
The CAS Registry Mumber 959392-22-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,9,3,9 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 959392-22:
(8*9)+(7*5)+(6*9)+(5*3)+(4*9)+(3*2)+(2*2)+(1*2)=224
224 % 10 = 4
So 959392-22-4 is a valid CAS Registry Number.
959392-22-4Relevant articles and documents
PURE DULOXETINE HYDROCHLORIDE
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Page/Page column 12, (2008/06/13)
Chemically and/or enantiomerically pure duloxetine HCl and process for preparing chemically and/or enantiomerically pure duloxetine HCl are provided. (Formul I)
